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H H S Department of Health and Human Services
U.S. Department of Health and Human Services
Health Resources and Services Administration

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Healthcare Systems Bureau

The Healthcare Systems Bureau (HSB) protects the public health and improves the health of individuals through an array of programs that provide national leadership and direction in targeted areas.

Organ Donation and Transplantation

HSB's Organ Donation and Transplantation programs extend and enhance the lives of individuals with end-stage organ failure for whom an organ transplant is the most appropriate therapeutic treatment. 

Key elements of the program are

  • Organ Procurement and Transplantation Network (OPTN), the national system that allocates and distributes donor organs to individuals waiting for an organ transplant;
  • Scientific Registry of Transplant Recipients (SRTR), a national database of statistics related to solid organ transplantation -- kidney, liver, pancreas, intestine, heart, and lung; and
  • Efforts to increase the supply of donor organs made available for transplantation.

C.W. Bill Young Cell Transplantation Program

The C.W. Bill Young Cell Transplantation Program provides support to patients who need a potentially life-saving bone marrow transplant or cord blood transplant. For some patients who have leukemia, lymphoma, sickle cell anemia or other inherited metabolic or immune system disorders, a marrow or cord blood transplant may be their best chance to live longer, healthier lives.

The National Cord Blood Inventory (NCBI) is charged with building a genetically and ethnically diverse inventory of 150,000 new units of high-quality umbilical cord blood for transplantation. These cord blood units, as well as other units in the inventories of participating cord blood banks, are made available to physicians and patients for blood stem cell transplants through the C. W. Bill Young Cell Transplantation Program, which is authorized by the same law. 

Poison Control Program

The Poison Control Program makes grants to regional poison centers to help them prevent and provide treatment recommendations for poisonings. The program also conducts a national poisoning awareness and prevention campaign and operates the toll-free Poison Help line (800-222-1222), a national number that connects callers with their poison center.

340B Drug Pricing Program

The Office of Pharmacy Affairs administers the 340B Drug Pricing Program, which reduces the cost of covered outpatient drugs for certain federally-supported entities and safety net hospitals. Manufacturers who participate in Medicaid are required to charge a price that will not exceed the amount determined under statute (ceiling price) when selling covered outpatient drugs to 340B covered entities. For more information, visit 340B Drug Pricing Program & Pharmacy Affairs.

Injury Compensation Programs

Two HRSA programs give individuals harmed by vaccines and, in the case of declared national health emergencies, other medical interventions, a streamlined system for compensation for their injuries.

The National Vaccine Injury Compensation Program provides compensation to people found to be injured by certain vaccines given routinely to children and adults, such as seasonal flu vaccine, measles, mumps, rubella or polio.

The Countermeasures Injury Compensation Program provides compensation to individuals for serious physical injuries or deaths from pandemic, epidemic, or security countermeasures, such as the 2009 pandemic H1N1 influenza vaccine (swine flu vaccine) and treatments.

Hansen’s Disease (Leprosy) Program

The National Hansen’s Disease Program (NHDP) has cared for people with Hansen’s Disease (leprosy) and related conditions since 1921. The Program provides medical care to any patient living in the United States or Puerto Rico through direct patient care at its facilities in Louisiana, an inpatient program in Hawaii, and 11 regional outpatient clinics.  Currently there are 2,888 patients care for through the NHDP’s outpatient clinics. The Program also provides training to health professionals, and conducts scientific research at the world’s largest and most comprehensive laboratory dedicated to Hansen’s Disease. The Program is the only dedicated provider of expert Hansen’s Disease treatment services in the United States and a crucial source of continuing education for providers dealing with the identification and treatment of the disease in the United States. 

Research conducted by the NHDP has led to the development and implementation of sophisticated cell and molecular biology tools used to study human disease. NHDP plays an integral role in the quest for a more complete understanding of Hansen's disease and translation of basic research findings into an internationally coordinated program designed to improve prevention and treatment.

Developed by the National Hansen's Disease Program, Lower Extremity Amputation Prevention (LEAP) is a comprehensive program that can dramatically reduce lower extremity amputations in individuals with Hansen's disease or any condition that results in loss of protective sensation in the feet.

Did You Know?
  • Today and every day, about 77 people in the U.S. receive an organ transplants and 19 people die waiting for a donated organ. 
  • At any given time, 6,000 patients are searching for a matched marrow donor or cord blood unit.
  • By participating in the 340B Drug Pricing Program, enrolled safety net providers may purchase certain medications at significant discounts for use with their eligible patients.
  • More than $1.8 billion has been awarded to 2,428 Vaccine Injury Compensation Program claimants since 1989.
  •  More than 70 percent of poisonings can be managed by a poison control center over the phone, avoiding unnecessary emergency room visits and reducing health care costs.