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Office of Pharmacy Affairs
Health Resources and Services Administration
5600 Fishers Lane, 08W05A
Rockville, MD 20857

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340B Drug Pricing Program

HRSA/OPA recently conducted a Welcome webinar for newly enrolled 340B registrants. Topics covered in this webinar includes,

  • Introduction to 340B program
  • 340B Historical legislation
  • Certification/Termination
  • Audit/340B program compliance
  • 340B educational resources

pictures of prescription drugsThe 340B Program enables covered entities to stretch scarce Federal resources as far as possible, reaching more eligible patients and providing more comprehensive services.

Manufacturers participating in Medicaid, agree to provide outpatient drugs to covered entities at significantly reduced prices.

Eligible health care organizations/covered entities are defined in statute and include HRSA-supported health centers and look-alikes, Ryan White clinics and State AIDS Drug Assistance programs, Medicare/Medicaid Disproportionate Share Hospitals, children’s hospitals, and other safety net providers. See the full list of eligible organizations/covered entities.

To participate in the 340B Program, eligible organizations/covered entities must register and be enrolled with the 340B program and comply with all 340B Program requirements. Once enrolled, covered entities are assigned a 340B identification number that vendors verify before allowing an organization to purchase 340B discounted drugs.

New registrations are accepted October 1-15, January 1-15, April 1-15 and July 1-15. 

 Click this image to sign up for 340B e-mail updates


Manufacturers are asked to review their 340B Database records and submit a Manufacturer Change Request Form (PDF - 28 KB) to if any updates are necessary. Ensuring the accuracy of information on file with HRSA will facilitate the rollout of the enhanced 340B pricing system later this year.

Notice to 340B Covered Entities Regarding Baxalta's VONVENDI (PDF - 34 KB) (September 2016)

340B Notice Regarding Limited Distribution Plan for Imbruvica (ibrutinib) (PDF - 87 KB) (August 2016)

Contract Pharmacy: Important Tips (August 2016)

Recertify your 340B registration every year

Contact the 340B Prime Vendor Program

340B Prime Vendor Program website
1-888-340-2787 (Monday – Friday, 9 a.m. – 6 p.m. ET)