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H H S Department of Health and Human Services
Health Resources and Services Administration
Health Resources and Services Administration

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Sexually Transmitted Disease Clinics


The US Department of Health and Human Services' Center for Disease Control and Prevention (CDC) oversees and funds the prevention of STDs. STD funding is authorized under section 318 of the Public Health Service Act (42 USCS§247). The goal of the program is to reduce morbidity and mortality by preventing cases and complications of STDs.

In order to be eligible for the 340B Program, an STD clinic must receive direct or in-kind Section 318 (42 USCS §247c) funding from their state or local health departments through the Sexually Transmitted Disease Control program administered by the Centers for Disease Control and Prevention.

The Office of Pharmacy Affairs (OPA) will reach out to the state STD program manager in order to verify the STD clinic is receiving Section 318 funding. OPA encourages each clinic to reach out to their state STD program manager before registering for the 340B Program to ensure they are receiving Section 318 funding. This is also a good time to confirm your Federal Grant Number, which is required during registration.


Registration Tips Step 1.Check your registration. Search the covered entities database to make sure you are not already registered. 

Registration Tips Step 2. Be aware of the latest registration dates and deadlines. The current registration periods are listed on the top right corner of this page, along with a link to the OPA database and registration forms. The registration forms are open only during the registration periods.

Registration Tips Step 3.Collect needed information. You will need to supply your Medicaid billing number or National Provider Identifier (if you will be billing Medicaid for drugs purchased at 340B prices), as well as basic information such as your mailing address and point of contact. Your Federal Grant Number is also required during registration. This number is 14 or 16 digits (sample: 1H25PS004661-01), and is not the same as your Funding Opportunity Announcement number. OPA no longer accepts the format of "STD-*State*" as the Federal Grant Number. Your registration will be deleted if you do not include your Federal Grant Number. Contact your state or local STD program manager if you are unsure of your number.

Registration Tips Step 4.Identify your Authorizing Official. Only an individual who can bind the organization to a contract, such as a CEO, COO, CFO, clinic administrator, or program manager can submit the 340B on-line registration, although you can designate another employee (not a consultant or contractor) to be the primary contact.

Registration Tips Step 5.Prepare to complete in one session. The authorizing official must complete the on-line registration in one session. If left inactive, the session will close and you will need to start over.

Once approved, an e-mail will be sent to the address provided on your registration. The message will confirm your successful enrollment in the 340B program and will include the date on which you can begin purchasing 340B discounted drugs and the 340B identification number that manufacturers, wholesalers and others will use to verify your participation in the 340B program

Registration Now

RegisterStart Date
January 1-15April 1
April 1-15July 1
July 1-15October 1
October 1-15January 1
Contact the 340B Prime Vendor Program

340B Prime Vendor Program website
1-888-340-2787 (Monday – Friday, 9 a.m. – 6 p.m. ET)