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Performance Review
 

Clinical Measures for Ryan White Part C: Early Intervention Services


HIV Clinical Performance Measure: # 2
Stated Performance Measure: Percentage of clients with HIV infection who had a CD4+ test done at least every 6 months
Numerator: Number of clients who had CD4+ counts measured at least twice in the measurement year, <6 months apart
Denominator: Number of clients with HIV infection who were seen within the measurement year
Data Sources:
  • Electronic Medical Record/Electronic Health Record
  • CAREWare, Lab Tracker, or other electronic data base
  • HIVQUAL reports on this measure for grantee under review
  • Medical record data abstraction by grantee of a sample of records that is negotiated with the OPR Review Team
National Goals, Targets, or Benchmarks for Comparison
  • IHI Goal: 90%[1]
  • National HIVQUAL Data: [2]

     
    2003
    2004
    2005
    Top 10%
    87.2%
    87.7%
    90.3%
    Top 25%
    74.2%
    78.0%
    76.6%
    Median*
    61.0%
    62.7%
    63.9%
Basis for Selection:
The CD4+ cell count plays a vital role in determining the staging of HIV disease and indicating the need for prophylaxis against opportunistic infections. It continues to be used in decisions regarding initiation or adjustment of antiretroviral treatment.
The most recent CD4+ cell count is the strongest predictor of subsequent disease progression and survival, according to clinical trials and cohort studies data on patients receiving antiretroviral therapy. [3]
US Public Health Guidelines:
"In general, CD4+ count should be determined every three to six months to (1) determine when to start
antiretroviral in patients who do not meet the criteria for initiation; (2) assess immunologic response to
antiretroviral therapy; and (3) assess the need for initiating chemoprophylaxis for opportunistic infections."3 (10/10/06)
References/Notes:
1 IHI Measure reads, “Percent of Patients/Clients with a CD4 Count Test in the Past 4 Months”
(http://www.ihi.org/IHI/Topics/HIVAIDS/HIVDiseaseGeneral/Measures/Percentof+patientswithaCD4counttestinthepast4months.htm)
2 Data is for a measure that looks at the percent of clients who have a CD4+ count done every four months, not every six months.
(http://www.hivguidelines.org/admin/files/qoc/hivqual/proj%20info/HQNatlAggScrs3Yrs.pdf)
3 Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents (http://aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf)
The Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents (the Panel), a working group of the Office of AIDS Research Advisory Council, develops these guidelines, which outline current understanding of how clinicians should use antiretroviral drugs to treat adults and adolescents with HIV infection. The Panel considers new evidence and adjusts recommendations accordingly. The guidelines for the frequency of CD4+ and Viral Load testing have changed over time. The measure on this detail sheet reflects the Guidelines as of October 2006.