What We Do


HRSA supports PEPFAR to deliver on its goal of an AIDS-free generation. HRSA’s Office of Special Health Initiatives, Office of Global Health implements the agency's PEPFAR activities. The global HIV/AIDS activities began in 2001 and vastly expanded in 2003 after the enactment of PEPFAR.

Since 2003, HRSA has been a significant contributor to PEPFAR's achievements. HRSA's work builds on the agency’s domestic and international experience and expertise by improving outcomes along the treatment and prevention cascade for people living with HIV.


In alignment with PEPFAR's mission to end the epidemic, HRSA's global efforts to support the delivery of HIV/AIDS care and treatment are underpinned by a commitment to building sustainable health care systems, especially through the provision of technical support, training, and assistance. This work is guided and reinforced by HRSA's experience building and strengthening the United States health system and leading the nation's response to the HIV epidemic by ensuring that each person living with HIV receives comprehensive care and treatment. Building on this experience, a major component of HRSA's global efforts is related to ensuring the quality of services, building and strengthening local organizations, and ensuring the production and readiness of a strong health care workforce across many cadres of facility and community service providers.

HRSA's Global PEPFAR Mission

HRSA’s Global PEPFAR mission is focused on:

  1. Quality: supporting the delivery of quality HIV/AIDS care and treatment services
  2. Access: providing training and technical assistance to build and strengthen all levels of the health sector
  3. Partnership: collaborating to build skills and support host countries, civil society and organizations
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