340B Office of Pharmacy Affairs Information System

HRSA places a high priority on the integrity of the 340B Program and uses existing authorities to provide oversight to both covered entities and manufacturers. In the fall of 2017, and in accordance with the statute, HRSA launched a new, integrated information system that focuses on three key priorities: security; user accessibility and accuracy.  The 340B Office of Pharmacy Affairs Information System (340B OPAIS) increases the integrity and effectiveness of 340B covered entity and manufacturer information. Authorized users of 340B OPAIS have a user account with appropriate roles and permissions granted by HRSA. 

340B Office of Pharmacy Affairs Information
System access to covered entity and manufacturer records, user accounts, change requests, recertification, and registrations

340B OPAIS System Highlights

Educational Resources

340B OPAIS Online Help for Public Users

340B OPAIS FAQs

Date Last Reviewed:  July 2018


340B OPAIS News

Welcome to the new 340B Office of Pharmacy Affairs Information System (340B OPAIS), a system with upgraded security and user functionality features. Information related to the 340B OPAIS will be submitted via electronic communication and featured on this page.