340B Office of Pharmacy Affairs Information System

In accordance with Section 340B(d)(1)(B) of the Public Health Service Act, HRSA is required to collect information from manufacturers to verify the accuracy of 340B ceiling prices, and then make ceiling prices available to covered entities. To this end, HRSA has developed a new, integrated information system that focuses on three key priorities: security, user accessibility, and data accuracy.

The 340B registration and pricing databases are collectively known as the 340B Office of Pharmacy Affairs Information System (340B OPAIS). Authorized users of 340B OPAIS must have a user account with appropriate roles and permissions granted by HRSA.

Access the 340B Office of Pharmacy Affairs Information System.

340B OPAIS System Highlights

Educational Resources

340B OPAIS Online Help for Public Users

340B OPAIS FAQs

Date Last Reviewed:  January 2019


340B OPAIS News

Welcome to the new 340B Office of Pharmacy Affairs Information System (340B OPAIS), a system with upgraded security and user functionality features. Information related to the 340B OPAIS will be submitted via electronic communication and featured on this page.